Captopril effect on non-diabetic glomerular albuminuria

In order to evaluate captopril effectiveness in the treatment of glomerular albuminuria in nondiabetic patients, an initial study was carried out in 16 patients with proteinuria greater than 1 gr/1, administering captopril, 50 mg/day during a 4 month follow-up period. During that time, urinary albumin levels significantly descended (p < 0.001), with a concomitant rise in serum albumin. We conclude that captopril can be effective as a part of the treatment of albuminuria associated with nephropathy of non diabetic origin.