Related Experiment Video
Updated: Jul 5, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
[Antihypertensive treatment compliance and obstacles to its improvement. Results of Russian program ARGUS-2]
Insights
Patient adherence to arterial hypertension treatment is low, with forgetting being a primary cause of missed doses. Improving patient education, motivation, and physician communication is crucial for better compliance.
Area of Science:
- Cardiology
- Public Health
- Patient Adherence Research
Background:
- Arterial hypertension (AH) management requires consistent patient adherence to antihypertensive medications.
- Understanding patient-perceived barriers is essential for optimizing treatment outcomes.
Purpose of the Study:
- To investigate the barriers encountered by patients in adhering to adequate treatment for arterial hypertension.
Main Methods:
- The ARGUS-2 trial involved an anonymous questionnaire survey of 1298 patients (outpatients and inpatients) across 13 Russian cities.
- Patients reported on life challenges with hypertension, medication compliance, reasons for missed doses, and drug intake opposition.
Main Results:
- Only 37.4% of patients were consistent treatment adopters.
- Forgetting was the most common reason for missed antihypertensive drug intake.
- Patients prioritized AH complications as major life problems, unlike physicians who focused on financial/routine issues. Poor self-control and lack of awareness regarding side effects were key barriers.
Conclusions:
- Improving patient compliance necessitates a multifaceted approach.
- Key strategies include enhanced patient education, increased motivation, active patient involvement in treatment, and improved physician-patient communication.
Aim:
To study barriers made by the patients for adequate treatment of arterial hypertension.
Material And Methods:
The ARGUS-2 trial was made in 15 centers of 13 cities of Russia. Anonymous questionnaire survey covered 1298 patients (796 outpatients and 502 inpatients). The patients answered the following questions: 1) what are basic problems of life with hypertension; 2) compliance with intake of antihypertensive drugs; 3) causes of missed intakes of the drugs; 4) opposition to intake of drugs by the patients. Questioning procedure was preset by the trial protocol.
Results:
Only 37.4% (38.9% outpatients, 34.6% inpatients) were the treatment adopters. Drug intake was missed most frequently because offorgetting. The problems of life with hypertension were differently interpreted by patients and physicians: for the latter main problems were financial and routine while AH complications were on the 6-7 place. The latter were of primary importance for the patients while financial problems took place 4-6 Barriers to regular intake for the patients were poor self-control and unawareness about side effects of the drugs.
Conclusion:
Complience of the patient can be improved only by complex approach: improvement of education, higher motivation, active involvement of patients into the treatment process, better contacts between the physician and the patient.
Related Concept Videos
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension V: Nursing Management
Atherosclerosis III: Management
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Antihypertensive Drugs: Angiotensin II Receptor Blockers
Errors occurring during blood pressure monitoring
Several factors...