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Frequency of primary solid malignant neoplasms in different age groups as seen in our practice
Zubair Ahmed1, Najamul Sahar Azad, Fouzia Rauf
1Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi.
Summary
This study analyzed 20,000 surgical biopsies to find cancer types by age and sex. Malignant neoplasms were most frequent in the fifth and sixth decades of life.
Area of Science:
- Oncology
- Pathology
- Epidemiology
Background:
- Understanding the incidence of primary solid malignant neoplasms is crucial for public health.
- Histologic typing and age-specific frequencies are key for targeted cancer control strategies.
Purpose of the Study:
- To determine the frequency of various histologic types of primary solid malignant neoplasms.
- To analyze these frequencies in males and females across different age groups.
Main Methods:
- Retrospective analysis of 20,000 consecutive surgical biopsies.
- Data collected from the section of histopathology at AKU in 2004.
Main Results:
- Malignant neoplasms are most common in the fifth and sixth decades of life.
- Specific common cancers varied by age and sex, including Hodgkin's lymphoma, Wilm's tumor, osteosarcoma, Ewing's sarcoma/PNET, colorectal adenocarcinoma, breast ductal carcinoma, oral cavity squamous cell carcinoma, and prostatic adenocarcinoma.
Conclusions:
- Malignant neoplasms show a peak incidence in the fourth, fifth, and sixth decades of life.
- Age and sex are significant factors in the distribution of primary solid malignant neoplasms.
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