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Paediatric Hepatic Haemangioma-A Rare Cause Of Pyrexia Of Unknown Origin
Hanana Nasir1, Hassan Bashir1, Iqra Asghar1
1Pakistan Kidney and Liver Institute and Research Center, Lahore, Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|March 23, 2025
Summary
Pyrexia of unknown origin (PUO) can be caused by rare conditions like hepatic hemangioma (HH) in children. This case highlights HH as a treatable cause of persistent fever and abdominal pain, resolved by surgery.
Area of Science:
- Pediatric Gastroenterology
- Hepatology
- Diagnostic Challenges
Background:
- Pyrexia of unknown origin (PUO) presents a significant diagnostic challenge due to its diverse and often elusive etiologies.
- Hepatic hemangioma (HH), a common benign liver tumor in children, is typically associated with vague abdominal pain and not commonly considered a cause of PUO.
Observation:
- A 4-year-old female presented with persistent low-grade fever and dull abdominal pain, initially posing a diagnostic dilemma.
- Extensive investigations were conducted to determine the cause of her prolonged fever.
- A drop in hemoglobin levels suggested a potential bleeding complication associated with the hepatic lesion.
Findings:
- The patient was diagnosed with hepatic hemangioma presenting as a cause of PUO.
- Treatment with prednisolone effectively reduced inflammatory markers.
- Surgical intervention (hepatectomy) was successfully performed, leading to the resolution of both the hepatic hemangioma and the pyrexia of unknown origin.
Implications:
- This case underscores the importance of considering uncommon causes, such as hepatic hemangioma, in the differential diagnosis of pediatric PUO.
- Early recognition and appropriate management of hepatic hemangioma can lead to favorable outcomes, resolving complex fevers.
- Highlights the successful integration of medical and surgical management for challenging pediatric cases.
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