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Primary synovial sarcoma of the kidney
Shiu-Dong Chung1, Kuo-How Huang, Shih-Chieh Chueh
1Department of Urology, Far Eastern Memorial Hospital, Ban Ciao, and Department of Urology, National Taiwan University Hospital, Taipei, Taiwan.
Summary
Primary renal synovial sarcoma is a rare kidney cancer. This study highlights two cases initially misdiagnosed as renal cell carcinoma, emphasizing awareness of this rare malignancy.
Area of Science:
- Oncology
- Pathology
Background:
- Primary synovial sarcoma of the kidney is an exceptionally rare malignancy.
- It is often misdiagnosed as renal cell carcinoma due to overlapping clinical and imaging features.
Observation:
- Two female patients, aged 30 and 49, presented with symptoms suggestive of renal masses.
- Initial diagnostic imaging revealed cystic and heterogeneous tumors, respectively.
- Both patients underwent radical nephrectomy with minimally invasive techniques.
Findings:
- Histopathological and immunohistochemical analyses confirmed primary renal synovial sarcoma in both cases.
- The tumors exhibited characteristic features of synovial sarcoma, including spindle and epithelial cells.
- Both patients remained recurrence-free at 15 and 27 months post-surgery.
Implications:
- This report underscores the importance of considering rare diagnoses like renal synovial sarcoma in cystic renal masses.
- Enhanced physician awareness is crucial for accurate and timely diagnosis.
- Early detection and surgical management are vital for favorable patient outcomes in this rare kidney cancer.
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