Related Experiment Video
Updated: Jul 5, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
Published on: September 17, 2017
Nuclear magnetic resonance-based modeling and refinement of protein three-dimensional structures and their complexes
Gloria Fuentes1, Aalt D J van Dijk, Alexandre M J J Bonvin
1Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Abstract:
Nuclear magnetic resonance (NMR) has become a well-established method to characterize the structures of biomolecules in solution. High-quality structures are now produced, thanks to both experimental and computational developments, allowing the use of new NMR parameters and improved protocols and force fields in structure calculation and refinement. In this chapter, we give a short overview of the various types of NMR data that can provide structural information, and then focus on the structure calculation methodology itself. We discuss and illustrate with tutorial examples both "classical" structure calculation and refinement approaches as well as more recently developed protocols for modeling biomolecular complexes.
More Related Videos
Related Concept Videos
Proteomics
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Applications Of NMR In Biology
The...
Protein Organization
The primary structure of a protein is its amino acid sequence.

