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Updated: Sep 9, 2025
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Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
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Updates to the CASP Infrastructure in 2024
Andriy Kryshtafovych1, Maciej Milostan2, Marc F Lensink3
1Genome Center, University of California, Davis, Davis, California, USA.
Proteins
|September 2, 2025
Summary
The Critical Assessment of Structure Prediction (CASP) data system was updated for CASP16, handling new categories and integrating with the Critical Assessment of Predicted Interactions (CAPRI) system to advance macromolecular structure prediction.
Area of Science:
- Computational biology
- Structural biology
- Bioinformatics
Background:
- The Critical Assessment of Structure Prediction (CASP) is a community experiment to assess the state-of-the-art in macromolecular structure prediction.
- The CASP data management system requires continuous evolution to meet the demands of these experiments.
Purpose of the Study:
- To detail the infrastructure enhancements for the CASP16 experiment.
- To document the integration of CASP and CAPRI (Critical Assessment of PRedicted Interactions) systems.
Main Methods:
- Expanding the CASP data handling infrastructure.
- Incorporating support for newly introduced and pilot categories from CASP15.
- Integrating the CASP and CAPRI data management systems.
Main Results:
- The CASP data management system was successfully expanded for CASP16.
- New categories and pilot categories from CASP15 are now fully supported.
- The CASP and CAPRI systems are now integrated.
Conclusions:
- The updated CASP data management system effectively supports the evolving needs of macromolecular structure prediction experiments.
- The integration with CAPRI facilitates a more comprehensive assessment of predicted interactions alongside structure prediction.
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