An overview of statistical issues and methods of meta-analysis
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Updated: Sep 28, 2026

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)
Published on: November 27, 2019
J E Schmid1, G G Koch, L M LaVange
1Department of Biostatistics, School of Public Health, University of North Carolina, Chapel Hill 27599-7400.
Abstract:
A meta-analysis is a statistical analysis of the data from some collection of studies in order to synthesize the results. In this paper we discuss issues that frequently arise in meta-analysis and give an overview of the methods used, with particular attention to the use of fixed- and random-effects approaches. The methods are then applied to two sample datasets.
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