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Research in patients with heart failure: challenges in recruitment

Susan J Pressler1, Usha Subramanian, Rose Mary Shaw

  • 1Indiana University School of Nursing in Indianapolis, IN, USA. SPressle@umich.edu

American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses
|May 3, 2008
PubMed

Insights

Recruiting patients with chronic heart failure for cognitive studies requires screening many individuals. High participation rates depend on efficient recruitment strategies at clinical sites.

Area of Science:

  • Cardiology
  • Neuropsychology
  • Clinical Research

Background:

  • Studies on heart failure patients often omit recruitment process details.
  • Understanding recruitment challenges is crucial for clinical trial success.

Purpose of the Study:

  • To detail the recruitment process for a chronic heart failure cognitive deficits study.
  • Focus on the initial 18 months of participant recruitment.

Main Methods:

  • Recruitment procedures were documented across two distinct clinical sites.
  • Eligibility screening involved echocardiograms and medical record review.

Main Results:

  • Site 1: 4,027 echocardiograms screened, 161 eligible, 29 participants (48% completion).
  • Site 2: 437 medical records screened, 163 eligible, 52 participants (74% completion).
  • Refusal rates were 23% (Site 1) and 21% (Site 2).

Conclusions:

  • Effective recruitment for heart failure studies necessitates screening a substantial patient cohort.
  • Tailored recruitment approaches may enhance participation rates.
Abstract

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