Related Experiment Video
Updated: Jul 5, 2026
04:40
Impact of Common Fruit Juices and Toothbrushing on the Discoloration of Primary Teeth
Published on: March 27, 2026
Accelerated tooth eruption in children with diabetes mellitus
Shantanu Lal1, Bin Cheng, Selma Kaplan
1Division of Pediatric Dentistry, Columbia University College of Dental Medicine, P&S 3-454c, 630W 168th St, New York, NY 10032, USA. sl784@columbia.edu
Pediatrics
|May 3, 2008
Summary
Children with diabetes experience faster tooth eruption, particularly during late mixed dentition. This accelerated eruption in pediatric diabetes warrants further investigation into potential oral health complications.
Area of Science:
- Pediatric Endocrinology
- Dental Development
- Metabolic Disorders
Background:
- Diabetes mellitus is a chronic metabolic disorder affecting various bodily systems.
- Dental development, including tooth eruption, can be influenced by systemic health conditions.
- Understanding these influences is crucial for comprehensive pediatric care.
Purpose of the Study:
- To investigate the relationship between diabetes mellitus and tooth eruption patterns in children aged 6-14.
- To compare tooth eruption timelines in children with and without diabetes.
- To identify potential correlations between diabetes-related factors and eruption speed.
Main Methods:
- A cohort study involving 270 children with diabetes and 320 controls.
- Assessment of tooth eruption status using standardized methods.
- Statistical analysis employing logistic regression models to evaluate associations.
Main Results:
- Children with diabetes showed accelerated tooth eruption during the late mixed dentition period (10-14 years).
- Girls exhibited significantly higher odds of advanced tooth eruption compared to boys in both groups.
- Gingival inflammation showed a trend towards association with expedited eruption; no link found with HbA1c or diabetes duration.
Conclusions:
- Diabetes in children is associated with accelerated tooth eruption.
- Further research is needed to explore links between eruption aberrations and dental complications like malocclusion and periodontal disease.
- Oral health promotion and disease prevention, including screening and referral, should be integrated into the care standards for children with diabetes.
Related Concept Videos
01:15Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
01:21Tooth Anatomy
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
01:19Type I Diabetes III: Clinical Manifestations
Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...
01:22Diabetes Mellitus: Overview and Type I Subtype
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
01:22Complications of Diabetes Mellitus
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
01:15Diabetes: Symptoms, Diagnosis, and Complications
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...