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Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination
15:25

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination

Published on: July 4, 2007

Descriptive epidemiology of dengue transmission in Uttar Pradesh

Piyush Tripathi1, Rashmi Kumar, Sanjeev Tripathi

  • 1Department of Pediatrics, King Georges Medical University, Lucknow, Uttar Pradesh, India.

Indian Pediatrics
|May 3, 2008
PubMed

Insights

Dengue infection surveillance in Lucknow revealed a 20.9% positivity rate in children with febrile illnesses. Dengue transmission occurs year-round, peaking post-monsoon, affecting both rural and urban areas equally.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Dengue infection poses a significant public health challenge, particularly in tropical and subtropical regions.
  • Understanding the epidemiological patterns of dengue is crucial for effective control strategies.

Purpose of the Study:

  • To investigate the epidemiology of dengue infection in Lucknow, India, over a three-year period.
  • To determine the prevalence and transmission patterns of dengue in pediatric populations.

Main Methods:

  • Hospital-based surveillance was conducted from 2003 to 2006.
  • Children presenting with acute febrile encephalopathy (AFE) and acute undifferentiated febrile illness (AUFI) were enrolled.
  • Dengue-specific IgM antibodies were detected using ELISA in acute serum samples.

Main Results:

  • A total of 118 out of 563 (20.9%) patients tested positive for dengue antibodies.
  • Dengue transmission was observed throughout the year, with a peak during the post-monsoon season.
  • The infection affected rural and urban areas equally, with no specific high-prevalence zones identified.

Conclusions:

  • Dengue is endemic in the Lucknow region, with consistent year-round transmission and a post-monsoon peak.
  • Both rural and urban populations are equally susceptible, highlighting the widespread nature of dengue transmission.
  • The findings underscore the need for sustained dengue surveillance and integrated vector management strategies in the region.

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