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Asthma and sinusitis: association and implication
Osamu Matsuno1, Emiko Ono, Ryuichi Takenaka
1Division of Respiratory Disease, Osaka Minami Medical Center, Kawachinagano City, Japan.
International Archives of Allergy and Immunology
|May 3, 2008
Summary
Sinusitis is common in asthma patients, with over a third experiencing it. Sinus issues, especially in adult-onset asthma, are linked to increased severity and complications, highlighting the importance of considering sinus health in asthma management.
Area of Science:
- Respiratory Medicine
- Otolaryngology
- Allergy and Immunology
Background:
- Sinusitis frequently co-occurs with asthma, but evidence linking the two is often based on symptoms alone.
- Previous studies lack robust clinical data, such as nasal endoscopic or CT findings, to support the association between sinusitis and lower airway disease.
Purpose of the Study:
- To investigate the impact of sinusitis on lower airway disease in patients with well-characterized asthma.
- To evaluate the relationship between asthma severity, sinusitis, and allergic rhinitis using objective clinical findings.
Main Methods:
- 188 asthma patients completed questionnaires on asthma, allergic rhinitis (AR), and sinus disease symptoms.
- 104 patients underwent clinical evaluation by an otorhinolaryngologist or sinus CT scans to diagnose sinusitis.
- Asthma patients were grouped based on the presence or absence of sinusitis and/or AR.
Main Results:
- Sinusitis prevalence in asthma patients was 36.7%; sinus CT abnormalities were found in 66.3%.
- Significant correlation observed between asthma severity and sinus morphologic abnormalities.
- Sinusitis often preceded asthma in adult-onset cases, while asthma preceded sinusitis in non-adult-onset cases, with higher complication rates in adult-onset asthma.
Conclusions:
- Bronchial asthma and sinusitis are closely related, with asthma onset age being a key factor in allergic disease frequency.
- Further research is needed to determine if sinus disease directly influences bronchial inflammation intensity.
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