[Control of the treatment with oral anticoagulants and prothrombin time]

There are many patients on oral anticoagulant therapy monitored with prothrombin time (Quick Test). Differences in sensitivity of the various types of tissue thromboplastins are the cause of the different results and common therapeutic ranges, calibrated reference thromboplastins with a defined International Sensibility Index (ISI) have become available. The ISI is used to estimate the International Normalized Rate (INR) which is used as a universal scale for the expression of the prothrombin time results in the control of oral anticoagulant therapy.