Related Experiment Video
Updated: Jul 5, 2026

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
Published on: January 7, 2019
Acute human immunodeficiency virus syndrome presenting with hemophagocytic lymphohistiocytosis
Kyung-Hwa Park1, Ho-Sung Yu, Sook-In Jung
1Department of Internal Medicine, Chonnam National University Hospital, 8 Hak-dong, Dong-gu, Gwangju 501-757, Korea.
Abstract:
Hemophagocytic lymphohistiocytosis (HLH) has been described in patients with advanced stages of human immunodeficiency virus (HIV) infection, but rarely occurs during the seroconversion stage of acute HIV infection. We report a case of acute HIV syndrome that presented with virus-associated HLH. The patient recovered spontaneously without any immunomodulating therapy. This case suggests that acute HIV infection should be included in the differential diagnosis of HLH and indicates that HLH associated with acute HIV infection can have a favorable outcome.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Cytomegalovirus Disease
Cryptococcal Meningitis
Sexually Transmitted Infections