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Related Experiment Videos

Mechanical pump dacryoreservoirs.

Juan Murube1, Gerd Geerling

  • 1Clinica Murube, Madrid, Spain.

Developments in Ophthalmology
|May 6, 2008
PubMed
Summary
This summary is machine-generated.

An implantable pump dacryoreservoir provides continuous artificial tear lubrication for severe dry eye patients, improving symptoms and allowing transplants. This method offers a safe and effective solution for ocular surface lubrication.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Tear Film Dynamics

Background:

  • Natural tear film is complex, making artificial tear reproduction difficult.
  • Severe dry eye requires frequent artificial tear application, with no overnight lubrication.
  • Previous continuous lubrication methods (spectacle-mounted, clothing-pocket reservoirs) had high infection risks.

Purpose of the Study:

  • To evaluate the safety and efficacy of an implantable pump dacryoreservoir for continuous ocular lubrication in severe dry eye patients.
  • To assess complications associated with implantable reservoirs through a Medline search.

Main Methods:

  • Implanted a 60-ml Medtronic reservoir in the abdominal wall subcutaneous tissue of 21 severe dry eye patients (Schirmer test <2mm/5min).
  • Connected reservoir via a silicone catheter to the upper conjunctival fornix.

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  • Evaluated results and complications via literature review.

    • Main Results:

    • All patients reported significant improvement in dry eye symptoms.
    • Ocular surface disease signs (keratopathy, conjunctival hyperemia) reduced; tear breakup time prolonged.
    • Two patients experienced skin ulceration from prominent catheter parts, managed successfully without infection.
    • No catheter reservoir infections observed; literature review indicated low infection rates for reservoirs.

    Conclusions:

    • The implantable pump dacryoreservoir is a safe and effective method for continuous ocular surface lubrication.
    • This technique enables corneal, conjunctival, or limbal transplantations in severe dry eye cases.