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Updated: Jul 5, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Erythroderma in a patient taking acitretin for plaque psoriasis
Jennifer Ahdout1, Hilary Mandel, Melvin Chiu
1Division of Dermatology, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, USA.
Abstract:
Acitretin is a second generation retinoid used in the treatment of psoriasis. It has shown particular efficacy in the treatment of pustular or erythrodermic psoriasis. A case of a patient who was being treated for plaque psoriasis with acitretin, who subsequently developed erythrodermic psoriasis is reported. The patient's erythroderma promptly resolved after discontinuing acitretin and initiating treatment with cyclosporine. Acitretin has been reported to induce erythrodermic psoriasis on occasion, but is more frequently reported as a treatment for it.
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