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Updated: Jul 5, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Atrial fibrillation and congestive heart failure
Noel G Boyle1, Kalyanam Shivkumar
1UCLA Cardiac Arrhythmia Center, Division of Cardiology, Department of Medicine, BH 407 CHS, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA. nboyle@mednet.ucla.edu
Insights
Atrial fibrillation (AF) and congestive heart failure (CHF) often coexist, complicating patient care. Newer therapies like biventricular pacing and radiofrequency ablation offer improved management strategies for these complex cardiac conditions.
Area of Science:
- Cardiology
- Cardiac Electrophysiology
Background:
- Atrial fibrillation (AF) and congestive heart failure (CHF) are prevalent cardiac conditions with significant comorbidity.
- The coexistence of AF and CHF exacerbates morbidity and mortality.
- Managing AF in CHF patients is challenging due to heightened risks associated with antiarrhythmic drug therapy.
Purpose of the Study:
- To review current treatment options for AF in patients with CHF.
- To assess the efficacy of novel therapies, including biventricular pacing for CHF and radiofrequency ablation for AF.
- To discuss findings from the AF-CHF study.
Main Methods:
- Literature review of existing treatment modalities for AF in CHF.
- Assessment of emerging therapies such as biventricular pacing and radiofrequency ablation.
- Analysis of data from the AF-CHF study (reported November 2007).
Main Results:
- The complex interplay between AF and CHF necessitates careful management.
- Antiarrhythmic drug therapy poses increased risks in patients with both conditions.
- Biventricular pacing and radiofrequency ablation represent newer therapeutic avenues.
Conclusions:
- Effective management of coexisting AF and CHF requires tailored strategies.
- Novel therapies show promise in improving outcomes for patients with both conditions.
- Further research and clinical evaluation are ongoing for these complex cardiac comorbidities.
Abstract:
Atrial fibrillation (AF) and congestive heart failure (CHF) are common cardiac conditions that frequently coexist. There is a complex interplay between the two conditions, with each increasing the morbidity and mortality associated with the other. The management of AF in patients with CHF requires special care because of the increased risk of antiarrhythmic drug therapy in the group. This report reviews current treatment options and assesses the role of the newer therapies of biventricular pacing for CHF and radiofrequency ablation for AF. It also discusses results of the AF-CHF study, which were reported in November 2007.
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