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Updated: Jul 5, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
[The relationships between ocular optical components and implications in the process of emmetropization]
E Yebra-Pimentel1, J M González-Méijome, C García-Resúa
1Escuela Universitaria de Optica y Optometría, Universidad Santiago de Compostela, Santiago de Compostela, España. eyebra@usc.es
Purpose:
To report the relationship between different optical ocular components and the influence of axial length on emmetropization.
Methods:
109 young university students, divided into five groups, were enrolled in this study: emmetropes, hyperopes, low myopes, moderate myopes and high myopes. Intraocular parameters and topographic corneal analyses were performed by ultrasonography and videokeratoscopy respectively.
Results:
Anterior chamber depth and axial length were found to correlate significantly in eyes with axial lengths less than 24 mm (r = 0.441; p < 0.001) However this correlation was not found in eyes with longer axial lengths (r = 0.098; p = 0.527). Lens thickness showed an inverse correlation with axial length for shorter eyes (r = 0.391; p < 0.001), whereas any correlation in longer eyes was associated with moderate to high levels of myopia. Anterior corneal curvature only correlated, although weakly, with vitreous chamber depth for shorter eyes (r = 0.363; p < 0.003).
Conclusion:
Differences in optical parameters of the human eye displayed different associations in longer eyes. A lack of correlation was seen between ocular components in eyes with higher myopia, corresponding to myopia in excess of 2.00 D.
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