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Evaluation of pressure support ventilation with seven different ventilators using Active Servo Lung 5000
Michihisa Terado1, Shingo Ichiba, Osamu Nagano
1Department of Emergency Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan. dr.tera@mac.com
Acta Medica Okayama
|May 10, 2008
Summary
This study compared 7 mechanical ventilators using Pressure Support Ventilation (PSV). The Puritan-Bennett 840 showed faster response, while the Evita series demonstrated gentler work of breathing during inspiration.
Area of Science:
- Critical Care Medicine
- Respiratory Physiology
- Biomedical Engineering
Background:
- Mechanical ventilation, particularly Pressure Support Ventilation (PSV), is crucial in critical care for managing acute respiratory insufficiency.
- Observed variations in patient recovery despite identical PSV settings necessitate evaluating ventilator performance differences.
- Understanding ventilator-specific responses is key to optimizing patient outcomes and mechanical ventilation strategies.
Purpose of the Study:
- To evaluate and compare the performance of 7 representative mechanical ventilators during Pressure Support Ventilation (PSV) using a respiratory simulation system.
- To quantify differences in ventilator response time, triggering effort, and work of breathing among various devices.
- To identify ventilators with superior rapid response and reduced work of breathing during PSV.
Main Methods:
- Utilized the Active Servo Lung 5000 (ASL5000) respiratory simulation system for standardized testing.
- Measured key performance parameters: inspiratory time delay (TD), pressure drop (DeltaPaw), work of breathing for triggering (WOBtrig), and total inspiratory work of breathing (WOBi).
- Compared these parameters across 7 distinct mechanical ventilator models under simulated PSV conditions.
Main Results:
- The Puritan-Bennett 840 (PB840) exhibited a significantly shorter mean time delay (TD) and lower work of breathing for triggering (WOBtrig) compared to other ventilators (p<0.01).
- The Evita series demonstrated the lowest inspiratory work of breathing (WOBi) among the tested ventilators, indicating gentler performance.
- The Servo-I and T-Bird ventilators showed higher WOBi values compared to the other models.
Conclusions:
- The PB840 is identified as the most rapid-response ventilator among those tested in the PSV mode.
- The Evita series is characterized as the gentlest mechanical ventilator concerning the total work of breathing during the inspiratory phase of PSV.
- These findings highlight significant performance variations among ventilators, impacting patient-specific responses during PSV.
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