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Updated: Jul 5, 2026

Induction of Acute Skeletal Muscle Regeneration by Cardiotoxin Injection
Published on: January 1, 2017
Exercise-induced stem cell activation and its implication for cardiovascular and skeletal muscle regeneration
Patrick Wahl1, Klara Brixius, Wilhelm Bloch
1Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University, Cologne, Germany.
Abstract:
A number of publications have provided evidence that exercise and physical activity are linked to the activation, mobilization, and differentiation of various types of stem cells. Exercise may improve organ regeneration and function. This review summarizes mechanisms by which exercise contributes to stem cell-induced regeneration in the cardiovascular and the skeletal muscle system. In addition, it discusses whether exercise may improve and support stem cell transplantation in situations of cardiovascular disease or muscular dystrophy.
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