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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: Jul 5, 2026

In vitro Labeling of Human Embryonic Stem Cells for Magnetic Resonance Imaging
11:41

In vitro Labeling of Human Embryonic Stem Cells for Magnetic Resonance Imaging

Published on: August 3, 2008

Stem cell labeling for magnetic resonance imaging.

Uwe Himmelreich1, Mathias Hoehn

  • 1In-vivo-NMR-Laboratory, Max Planck Institute for Neurological Research, Cologne, Germany.

Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy
|May 10, 2008
PubMed
Summary
This summary is machine-generated.

Magnetic resonance imaging (MRI) enables non-invasive monitoring of cell dynamics in vivo. Cell labeling is crucial for tracking stem cell migration in cell therapy, with this review exploring labeling strategies and contrast agents.

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Last Updated: Jul 5, 2026

In vitro Labeling of Human Embryonic Stem Cells for Magnetic Resonance Imaging
11:41

In vitro Labeling of Human Embryonic Stem Cells for Magnetic Resonance Imaging

Published on: August 3, 2008

Labeling hESCs and hMSCs with Iron Oxide Nanoparticles for Non-Invasive in vivo Tracking with MR Imaging
09:06

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Monitoring Dendritic Cell Migration using 19F / 1H Magnetic Resonance Imaging
08:12

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Published on: March 20, 2013

Area of Science:

  • Biomedical Imaging
  • Cell Biology
  • Regenerative Medicine

Background:

  • Non-invasive magnetic resonance imaging (MRI) is increasingly utilized for in vivo cell dynamics monitoring.
  • Tracking cell migration is vital for stem cell-based therapy strategies.

Purpose of the Study:

  • To review various cell labeling routes for in vivo imaging.
  • To discuss the potential for observing cell localization and function.
  • To highlight labeling strategy possibilities, contrast agents, and potential challenges.

Main Methods:

  • Review of existing literature on cell labeling techniques for MRI.
  • Analysis of different contrast agents and their properties.
  • Discussion of the advantages and disadvantages of various labeling strategies.

Main Results:

  • Cell labeling is essential for achieving excellent contrast in MRI for in vivo cell tracking.
  • Various labeling strategies exist, each with specific pros and cons.
  • Potential ambiguities and problems associated with cell labeling are identified.

Conclusions:

  • Effective cell labeling is key to successful in vivo cell dynamics monitoring using MRI.
  • Understanding labeling strategies and contrast agents is crucial for optimizing cell tracking in therapeutic applications.
  • Addressing potential labeling challenges is important for reliable in vivo cell function assessment.