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NCI-EORTC--10th Symposium--new approaches and cellular targets. 16-19 June 1998, Amsterdam, The Netherlands

L Kelland1

  • 1CRC Centre for Cancer Therapeutics, Institute of Cancer Research, Sutton, Surrey, UK. lloyd@icr.ac.uk

Idrugs : the Investigational Drugs Journal
|May 10, 2008
PubMed

Insights

This symposium highlighted advances in anticancer drug development, focusing on novel molecular therapies over traditional cytotoxic agents. Key research areas included emerging cellular targets for cancer treatment.

Area of Science:

  • Oncology
  • Pharmacology
  • Biotechnology

Background:

  • The symposium marked the tenth meeting in a 20-year series focused on anticancer agent research and development.
  • Historically, meetings emphasized cytotoxic agents, but recent trends show a shift towards biological and molecular therapies.

Purpose of the Study:

  • To present and discuss recent findings in the preclinical and early clinical research and development (R and D) of new anticancer agents.
  • To reflect current trends and opinions in the field of anticancer drug development.

Main Methods:

  • Presentation and discussion of research results.
  • Keynote sessions focused on new therapeutic approaches and cellular targets.
  • Review of preclinical and early clinical R and D data for novel anticancer agents.

Main Results:

  • A significant shift in focus from cytotoxic agents to biological/molecular-based therapies was observed.
  • Keynote sessions discussed novel cellular targets such as telomerase, apoptosis, and p53.
  • Some discussed targets, while innovative, were not entirely novel.

Conclusions:

  • The field of anticancer drug development is increasingly prioritizing molecular and biological targets.
  • Despite the emergence of new targets, some established targets remain central to ongoing research.
  • The symposium underscored the dynamic evolution of anticancer therapeutic strategies.

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