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Association mapping via a class of haplotype-sharing statistics

Andrew S Allen1, Glen A Satten

  • 1Department of Biostatistics and Bioinformatics, Duke University, Hock Plaza, Suite 1102, 2424 Erwin Road, Durham, North Carolina 27705, USA. andrew.s.allen@duke.edu

BMC Proceedings
|May 10, 2008
PubMed
Summary

Haplotype-sharing statistics improve genetic association mapping in case-parent trio data. These novel methods offer greater power and precision in localizing disease risk loci compared to single nucleotide polymorphism analysis.

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