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Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein01:20

Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein

Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...

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Related Experiment Video

Updated: Jul 5, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

Does the seizure frequency increase in Ramadan?

Yasemin B Gomceli1, Gulnihal Kutlu, Leyla Cavdar

  • 1Ministry of Health Ankara Training and Research Hospital, Department of Neurology, Ankara, Turkey. yasemingomceli@hotmail.com

Seizure
|May 13, 2008
PubMed
Summary
This summary is machine-generated.

Epileptic patients experienced a significant increase in seizure frequency during Ramadan fasting. Changes in drug regimens and daily rhythms were identified as key contributing factors to this heightened risk.

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Last Updated: Jul 5, 2026

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
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Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits
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Multi-system Monitoring for Identification of Seizures, Arrhythmias and Apnea in Conscious Restrained Rabbits

Published on: March 27, 2021

Area of Science:

  • Neurology
  • Clinical Pharmacy
  • Islamic Studies

Background:

  • Ramadan fasting involves abstaining from food, drink, and oral medications from dawn to sunset.
  • Epilepsy management requires consistent medication adherence for seizure control.

Purpose of the Study:

  • To investigate changes in drug regimens and seizure frequency among epileptic patients observing Ramadan fasts.
  • To identify factors influencing seizure occurrence during Ramadan.

Main Methods:

  • A cohort of 114 epileptic patients who fasted during Ramadan were studied retrospectively.
  • Seizure frequency during Ramadan was compared to pre-Ramadan periods (1 year and 3 months).
  • Risk factors, including drug regimen changes, were analyzed.

Main Results:

  • A statistically significant increase in seizure frequency was observed during Ramadan (p<0.001).
  • Patients who altered their drug regimens showed a higher risk of seizures (p<0.05).
  • No significant difference in seizure frequency was found between monotherapy and polytherapy groups (p>0.05).

Conclusions:

  • Ramadan fasting is associated with an increased seizure frequency in epileptic patients.
  • Alterations in drug pharmacokinetics/pharmacodynamics and daily rhythms likely contribute to reduced drug efficacy and increased seizures.
  • Careful medication management and patient counseling are crucial for epileptic individuals observing Ramadan.