[Radiologic findings in non-Wilms' renal tumors in children]

Area of Science:

• Pediatric Radiology
• Oncology
• Nephrology

Background:

• Non-Wilms' renal tumors are rare in children.
• Accurate radiologic characterization is crucial for diagnosis and management.
• Differentiating these tumors from Wilms' tumor is essential.

Purpose of the Study:

• To analyze and describe the radiologic findings of various non-Wilms' renal tumors in pediatric patients.
• To correlate imaging features with specific tumor types.
• To evaluate the utility of radiology in the diagnostic work-up.

Main Methods:

• Retrospective analysis of 26 pediatric patients with histologically confirmed non-Wilms' renal tumors.
• Evaluation of radiological variables including tumor size, location, margins, necrosis, hemorrhage, calcifications, and associated findings.
• Correlation of imaging findings with clinical presentation and patient age.

Main Results:

• Mesoblastic nephromas (11) presented as predominantly solid masses with ill-defined margins and necrosis.
• Multilocular cystic nephromas (7) showed multicystic masses with thickened septa and well-defined margins.
• Renal carcinomas (4) exhibited diverse features including calcifications and excretory tract infiltration.
• Other rare tumors like clear cell sarcoma, rhabdoid tumor, intrarenal neuroblastoma, and angiomyolipoma showed distinct radiologic characteristics.

Conclusions:

• Radiologic findings, combined with clinical and epidemiological data, are valuable for the diagnostic work-up of pediatric renal tumors.
• While imaging is highly informative, histological confirmation remains indispensable for definitive diagnosis.
• Understanding the spectrum of radiologic appearances aids in differentiating non-Wilms' tumors.