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Updated: Jul 5, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
[Fatal pulmonary embolism after embolization of a hepatocellular carcinoma using microspheres]
J J Noguera1, A Martínez-Cuesta, B Sangro
1Servicio de Radiología. Unidad de Hepatología. Clínica Universitaria de Navarra. Pamplona. España.
Abstract:
Intra-arterial treatment has become a first-line alternative in the therapeutic arsenal against primary and metastatic hepatic tumors. Despite its proven safety and efficacy, intra-arterial treatment with lipiodol, chemotherapy, and particles carries the risk of complications, some of which can be lethal. We present the case of a 32-year-old woman with multifocal hepatocellular carcinoma treated with microsphere embolization. After the second session, the patient died of a pulmonary embolism composed of particles and tumor cells.
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