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Updated: Jul 5, 2026

Sheathless Capillary Electrophoresis–Mass Spectrometry for Metabolic Profiling of Biological Samples
Published on: October 1, 2016
Sorbent preconcentration procedures coupled to capillary electrophoresis for environmental and biological
Patricia Puig1, Francesc Borrull, Marta Calull
1Department of Analytical Chemistry and Organic Chemistry, Rovira i Virgili University, Tarragona, Spain.
Abstract:
Sorbent preconcentration offers good strategies to overcome the poor detection limits of capillary electrophoresis (CE). The present review focuses on the recent trends of the coupling between sorbent preconcentration techniques, namely solid-phase extraction (SPE) and solid-phase microextraction (SPME), to capillary electrophoresis (CE). Special attention is given to their environmental and biological application. We also discuss the most important advantages and disadvantages of the different methodologies and briefly outline the new trends of the coupling between sorbent preconcentration and CE.
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