Related Experiment Video
Updated: Jul 5, 2026

Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals
Published on: July 10, 2015
Postdeployment evaluation of health risk communication after exposure to a toxic industrial chemical
James D Mancuso1, Margaret Ostafin, Mark Lovell
1Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Abstract:
Increasing emphasis is being placed on the appropriate communication of deployment-related risks among military service members. This report validates risk communication on the postdeployment health assessment (PDHA), in the context of a known, low-level exposure to a toxic industrial chemical. In late 2003, 245 soldiers were exposed to hexavalent chromium at an industrial site in Iraq; of those, 227 had completed PDHAs on file for review. Despite being directed to document this exposure upon redeployment, only 55 soldiers (24.2%) specifically reported chromium exposure. Increasing age and time at the industrial site were associated with increased reporting of exposure. Although providers documented deployment exposure concerns for only 65.4% of this population, this was much more often than for other redeploying service members. The PDHA is a risk assessment and risk communication tool that has sources of misclassification, and results must be interpreted with caution when individual or population occupational and environmental risks resulting from deployment are assessed.
Related Concept Videos
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity Testing in Animals
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Effects of Chemicals: Overview

