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Updated: Jul 5, 2026
06:35
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
[Polymyalgia rheumatica and giant cell arteritis: recent data and current situation].
1Division de rhumatologie, HUG, Beau-Séjour 1211 Genève.
Revue Medicale Suisse
|May 14, 2008
Summary
Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are inflammatory conditions in the elderly. Glucocorticoids are the primary treatment, with methotrexate and aspirin offering additional benefits.
Area of Science:
- Rheumatology
- Internal Medicine
- Geriatrics
Context:
- Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are common inflammatory conditions affecting the elderly.
- These diseases are often linked and require prompt diagnosis and management.
Purpose:
- To outline the diagnostic criteria and current treatment strategies for PMR and GCA.
- To discuss the role of imaging, corticosteroids, methotrexate, and aspirin in managing these conditions.
Summary:
- GCA diagnosis relies on temporal artery biopsy, but treatment should not be delayed due to risks of ischemic complications. PET-scan and MRI angiography can aid diagnosis.
- PMR diagnosis is primarily clinical, focusing on shoulder and hip girdle pain and stiffness.
- Both PMR and GCA are treated with glucocorticoids, with methotrexate as a potential corticosteroid-sparing agent. Low-dose aspirin may reduce ischemic events in GCA.
Impact:
- Provides a concise overview of PMR and GCA diagnosis and management for clinicians.
- Highlights the importance of timely intervention to prevent serious complications.
- Discusses emerging therapeutic options and their role in patient care.
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