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Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

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Published on: March 15, 2022

Anticoagulation in patients with heparin-induced thrombocytopenia undergoing percutaneous coronary angiography and

Alexander Joost1, Volkhard Kurowski, Peter W Radke

  • 1Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany. alexander.joost@uk-sh.de

Current Pharmaceutical Design
|May 14, 2008
PubMed

The administration of heparins (unfractionated or fractionated) represents the current standard as anticoagulant treatment during percutaneous coronary intervention in different clinical settings (elective cases and acute coronary syndrome). Since the incidence of heparin-induced thrombocytopenia (HIT) is expected to range between 0.1 and 5%, the application of an appropriate anticoagulant agent has become a mandatory issue. This review will provide current pathophysiological insights of HIT as well as contemporary alternative anticoagulant strategies during PCI in patients with or at risk of HIT.

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