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Updated: Jul 5, 2026
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Analysis of Schwann-astrocyte Interactions Using In Vitro Assays
Published on: January 13, 2011
[Biocompatibility study of polylactic/glycolic acid and Schwann cell]
Huaidong Du1, Hongbin Tian, Liang Zhou
1Department of Otorhinolaryngology, Affiliated Eye Ear Nose Throat Hospital of Fudan University, Shanghai, 200031, China.
Abstract
Objective:
To examine the biocompatibility of polylactic/glycolic acid (PLGA) and Schwann cells.
Method:
Schwann cells were harvested from rat brachial and sciatic nerves. Schwann cells were cultured with PLGA, observed by phase-contrast microscopy and electron microscopy.
Result:
Schwann cells could attach and proliferate on the surface of the PLGA.
Conclusion:
The PLGA has good cellular biocompatibility. It can be used as biomaterial for tissue engineering.
