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Do outcomes vary according to the source of admission to the pediatric intensive care unit?
Folafoluwa O Odetola1, Andrew L Rosenberg, Matthew M Davis
1Department of Pediatrics and Communicable Diseases, Division of Pediatric Critical Care Medicine, University of Michigan Health System, Ann Arbor, MI, USA. fodetola@med.umich.edu
Insights
Outcomes in pediatric intensive care units (PICUs) differ based on admission source. Strategies to reduce mortality should focus on patients transferred from hospital wards and other PICUs.
Area of Science:
- Pediatric Critical Care Medicine
- Healthcare Outcomes Research
- Hospital Administration
Background:
- Tertiary pediatric intensive care units (PICUs) manage critically ill children.
- Patient outcomes can be influenced by the origin of admission to the PICU.
Purpose of the Study:
- To investigate the relationship between the source of admission to a tertiary pediatric intensive care unit and patient mortality and length of stay.
- To identify specific admission sources associated with adverse outcomes.
Main Methods:
- Retrospective analysis of prospectively collected data from a tertiary medical center.
- Inclusion of all admissions to medical-surgical and cardiac PICUs over a six-year period.
- Multivariable regression analysis to compare mortality and length of stay, controlling for illness severity.
Main Results:
- 74% of admissions were direct (emergency department/operating room), while 26% were indirect (wards, interhospital transfers).
- Ward admissions were associated with significantly higher mortality odds (OR 1.65) and longer PICU stays (+4 days) compared to emergency department admissions.
- Inter-PICU transfers showed higher mortality odds (OR 1.43) and the longest PICU stays (+6 days), though not statistically significant.
Conclusions:
- Significant variations in tertiary pediatric intensive care outcomes exist based on admission source.
- Targeting interventions for patients admitted from hospital wards and inter-PICU transfers is crucial for reducing mortality.
Objective:
To examine associations between mortality, length of stay, and the sources of admission to tertiary pediatric intensive care.
Design:
A retrospective analysis of prospectively collected data.
Setting:
A tertiary medical center with a 16-bed medical-surgical intensive care unit and a 15-bed cardiac pediatric intensive care unit (PICU).
Patients:
All admissions from July 1, 1998, through June 30, 2004. Multivariable regression methods compared length of stay and mortality between the sources of PICU admission, controlling for multiple variables, including severity of illness.
Interventions:
None.
Measurements And Main Results:
Of 8,897 eligible admissions, 74% were directly from the study hospital's emergency department or operating rooms, while 26% were from indirect sources, including the study hospital's wards (11%) or interhospital transfer from either non-PICU (12%) or PICU settings (3%). Compared with emergency department admissions, ward admissions had higher odds of mortality (odds ratio 1.65, 95% confidence interval 1.08-2.51), transfer admissions from non-PICU settings did not have elevated odds of mortality (odds ratio 0.80, 95% confidence interval 0.51-1.25), and inter-PICU transfer admissions had higher odds of mortality (odds ratio 1.43, 95% confidence interval 0.80-2.56), although not reaching statistical significance. Compared with emergency department admissions, ward admissions stayed almost 4 days longer in the PICU, while interhospital transfer admissions from non-PICU and PICU settings stayed 2 and 6 days longer, respectively.
Conclusions:
Outcomes of tertiary pediatric intensive care vary significantly by source of admission. Strategies aimed at reduction of mortality at the tertiary PICU should target transfer admissions from the hospital's wards and from PICUs of other hospitals.
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