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Related Concept Videos

Production of Organic Acids01:25

Production of Organic Acids

Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
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Continuous fermentation is a key strategy in industrial ethanol production, particularly when efficiency, scalability, and high yields are essential. This approach allows for uninterrupted operation and optimized resource utilization. The primary feedstock, corn starch, undergoes enzymatic hydrolysis facilitated by α-amylase and glucoamylase. These enzymes break down the starch into fermentable sugars such as glucose, which are readily assimilated by fermentative microorganisms.Fermentation...
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Microbial Fermentation

Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
Fermentation01:29

Fermentation

Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism.
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Alkylation of β-Ketoester Enolates: Acetoacetic Ester Synthesis01:07

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Acetoacetic ester synthesis is a method to obtain ketones from alkyl halides and β-keto esters. The reaction occurs in the presence of an alkoxide base that abstracts the acidic proton of the β-keto esters. The step results in an enolate ion which is doubly stabilized. The enolate then reacts with an alkyl halide via the SN2 process to produce an alkylated ester intermediate with a new C–C bond. The hydrolysis of the intermediate, followed by acidification, results in an alkylated β-keto acid.
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Carboxylic Acids to Esters: Acid-Catalyzed (Fischer) Esterification Overview

The Fischer esterification reaction was developed by the German chemist Emil Fischer in 1895. It is a condensation reaction between carboxylic acids and alcohols in an acidic medium to give esters and water.

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A new process for acrylic acid synthesis by fermentative process.

B H Lunelli1, E R Duarte, E C Vasco de Toledo

  • 1Laboratory of Optimization, Project and Advanced Control, Department of Chemical Process, School of Chemical Engineering, State University of Campinas, P.O. Box 6066, 13083-970, Campinas, SP, Brazil.

Applied Biochemistry and Biotechnology
|May 15, 2008
PubMed
Summary

This study presents a new biotechnological process for producing acrylic acid from sugarcane fermentation. A deterministic model was developed to optimize this sustainable and efficient chemical synthesis route.

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Area of Science:

  • Biotechnology
  • Chemical Engineering
  • Biochemical Synthesis

Background:

  • Biotechnological processes offer diverse routes for synthesizing high-value chemical products.
  • Each route presents unique advantages regarding yield, productivity, separation, cost, and environmental impact.

Purpose of the Study:

  • To develop a deterministic model for the biochemical synthesis of acrylic acid.
  • To explore an alternative, sustainable process for acrylic acid production.

Main Methods:

  • Development of a deterministic model incorporating tubular reactor equations.
  • Utilizing a structured kinetic model for biochemical representation.
  • Focusing on continuous acrylic acid production from sugarcane fermentation.

Main Results:

  • A functional deterministic model for biochemical acrylic acid synthesis was established.
  • The proposed process enables continuous acrylic acid generation.
  • Sugarcane fermentation was identified as a viable feedstock.

Conclusions:

  • The developed deterministic model facilitates the exploration of alternative acrylic acid synthesis pathways.
  • Biotechnological production of acrylic acid from sugarcane fermentation offers a promising sustainable alternative.