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Radiotherapy: an effective treatment for extramammary Paget's disease.
1Regional Centre for Radiotherapy and Oncology, St Luke's Hospital, Guildford, Surrey.
Clinical Oncology (Royal College of Radiologists (Great Britain))
|January 1, 1991
Summary
Extramammary Paget's disease is rare. Radical radiotherapy effectively controlled the condition in four out of six patients, offering a viable treatment option for this uncommon skin cancer.
Area of Science:
- Oncology
- Dermatology
Background:
- Extramammary Paget's disease (EMPD) is a rare intraepithelial adenocarcinoma.
- Surgical excision, while standard, can lead to local recurrence or be challenging in elderly patients with extensive disease.
Purpose of the Study:
- To evaluate the efficacy of radiotherapy in managing extramammary Paget's disease.
Main Methods:
- Retrospective review of case records for six patients with extramammary Paget's disease treated with radiotherapy.
- Analysis of treatment outcomes and disease control.
Main Results:
- Radical radiotherapy to the skin achieved disease control in four out of the six reviewed patients.
- This suggests radiotherapy can be an effective treatment modality for EMPD.
Conclusions:
- Radiotherapy is a potentially effective treatment for extramammary Paget's disease, particularly when surgery is not optimal.
- Further research may explore its role in a multidisciplinary approach to EMPD management.