Head and neck extramedullary disease as the initial presentation of acute myelogenous leukemia in a child
Related Experiment Video
Updated: Jul 5, 2026

Murine Model of Leukemia Relapse to Induction Chemotherapy for Acute Lymphoblastic Leukemia
Published on: October 17, 2025
1Section of Pediatric Dentisty, The Ohio State University, Nationwide Children's Hospital, Columbus, Ohio, USA. Marcio.DaFonseca@NationwideChildrens.org
Abstract:
The purpose of this paper was to describe a child with a noncontributory medical history who sought an emergency dental appointment due to a significant facial and neck swelling. The clinical and radiographic exams revealed no odontogenic infection, and the patient was subsequently diagnosed with acute myelogenous leukemia by the hematology/oncology service. This report underscores the important role pediatric dentists can play in an early referral for further workup of a suspected malignancy, which may initially present as extramedullary disease in the head and neck.
Related Concept Videos
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...