Related Experiment Video
Updated: Jul 5, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Current sunscreen issues: 2007 Food and Drug Administration sunscreen labelling recommendations and combination
Camile L Hexsel1, Scott D Bangert, Adelaide A Hebert
1Department of Dermatology, Henry Ford Hospital, Detroit, Michigan, USA.
Abstract:
The Food and Drug Administration (FDA) regulates sunscreens as over-the-counter drugs. This article describes sunscreen actives available in the United States, new developments available elsewhere, and the amendment to the FDA 1999 sunscreen monograph, released on August 27, 2007, which proposes a new grading system for ultraviolet B protection, a cap of the sunburn protection factor to 50+, and a 4-star grading of ultraviolet A protection. In addition, current data on combination sunscreen and insect repellent products are discussed. Application of a combination product too frequently poses the risk of insect repellent toxicity, whereas application too infrequently invites photodamage. It may be prudent to follow the same approach of our Canadian colleagues of discontinuing combination products until more investigations are available.
Related Concept Videos
FDA Approved Drugs: Changes to Approved Drugs
Acne Infection
Drug Regulation
Clinically Relevant Drug Product Specifications: Methods of Establishment
Cancer Prevention
Some...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...

