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Updated: Jul 5, 2026
04:19
The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
Published on: January 13, 2023
Root development of immature third molars transplanted to surgically created sockets
Oskar Bauss1, Ioannis Zonios, Alexander Rahman
1Department of Orthodontics, University Dental School of Geneva, Geneva, Switzerland. o.bauss@praxisbauss.de
Summary
Transplanting immature teeth into surgically created sockets, especially at later developmental stages, impairs root development compared to fresh extraction sites. This may be due to damage to Hertwig's epithelial root sheath.
Area of Science:
- Dental surgery
- Regenerative dentistry
- Tooth transplantation
Background:
- Tooth transplantation is a treatment option for missing immature teeth.
- Root development after transplantation is crucial for long-term success.
- Surgical preparation of the recipient socket may influence outcomes.
Purpose of the Study:
- To compare root development of immature teeth transplanted into surgically created sockets versus fresh extraction sites.
- To evaluate the impact of socket preparation on post-transplantation root growth.
Main Methods:
- 64 immature third molars (root development stages 3-4) were transplanted in 62 patients.
- Teeth were transplanted into either surgically created sockets (n=22) or fresh extraction sites (controls, n=42).
- Root development was assessed via intraoral radiographs; extraoral storage time and handling were recorded.
Main Results:
- No significant differences in root development at stage 3.
- At stage 4, surgically created sockets showed significantly less root length and increment compared to controls (P=.025, P=.038).
- In prepared sockets (stage 4), longer extraoral storage and more handling correlated with reduced root length increment (r=-0.910, r=-0.775).
Conclusions:
- Surgically prepared sockets lead to impaired root development in advanced immature tooth transplants.
- Damage to Hertwig's epithelial root sheath during socket preparation is a potential cause.
- Careful surgical technique and minimizing extraoral time are important for successful tooth transplantation.
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