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Updated: Jul 5, 2026

Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes
Published on: May 31, 2011
Gene Regulation Ontology (GRO): design principles and use cases
Elena Beisswanger1, Vivian Lee, Jung-Jae Kim
1Jena University Language and Information Engineering (JULIE) Lab, Jena, Germany. elena.beisswanger@uni-jena.de
Abstract:
The Gene Regulation Ontology (GRO) is designed as a novel approach to model complex events that are part of the gene regulatory processes. We introduce the design requirements for such a conceptual model and discuss terminological resources suitable to base its construction on. The ontology defines gene regulation events in terms of ontological classes and imposes constraints on them by specifying the participants involved. The logical structure of the ontology is intended to meet the needs of advanced information extraction and text mining systems which target the identification of event representations in scientific literature. The GRO has just been submitted to the OBO library and is currently under review. It is available at http://www.ebi.ac.uk/Rebholz-srv/GRO/GRO.html.
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