Intratubular germ cell tumor. Relation with 'burned-out' tumor and testicular germinal neoplasia

The study of one case of a 'typical' testicular seminoma (1.2 cm in diameter) allows us to observe its association with extensive intratubular germ cell tumor (IGCT) and its correlation with a progressive sclerosis of the seminiferous tubules. Based upon this case, and after verification of morphologic, histochemical and immunohistochemical identities between the IGCT, the interstitial neoplastic cells and those from the seminoma, we speculate on the interrelation between the IGCT, the germinal testicular tumors, and the 'burned-out' tumor.