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Related Experiment Videos

Multiple-needle insertion method in percutaneous ethanol injection therapy for liver neoplasms.

S Shiina1, Y Hata, Y Niwa

  • 1Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.

Gastroenterologia Japonica
|February 1, 1991
PubMed
Summary

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Percutaneous ethanol injection therapy (PEIT) can be lengthy. A new multiple-needle technique significantly reduces treatment sessions for PEIT, offering a more efficient therapeutic option.

Area of Science:

  • Hepatology
  • Interventional Radiology
  • Oncology

Background:

  • Percutaneous ethanol injection therapy (PEIT) is a common treatment for liver tumors.
  • A limitation of PEIT is the high number of sessions required for effective treatment.
  • Reducing treatment sessions can improve patient compliance and reduce healthcare costs.

Purpose of the Study:

  • To evaluate the efficacy of a novel multiple-needle insertion technique for PEIT.
  • To determine if this method can reduce the number of treatment sessions required.
  • To assess the safety and tolerability of the multiple-needle PEIT method.

Main Methods:

  • A multiple-needle insertion technique was developed, involving the placement of two or three needles prior to ethanol injection.

Related Experiment Videos

  • The efficacy of this method was compared to the conventional single-needle PEIT approach.
  • Histopathologic examination, imaging, and serum alpha-fetoprotein levels were used to assess treatment outcomes.
  • Patient-reported side effects such as pain, fever, and intoxication were monitored.

    • Main Results:

    • The multiple-needle insertion method markedly reduced the number of treatment sessions needed.
    • Histopathology, imaging, and alpha-fetoprotein levels confirmed the efficacy of the multiple-needle technique.
    • No serious complications were observed with the new method.
    • Transient side effects like pain, fever, and intoxication were comparable to the conventional method.

    Conclusions:

    • The multiple-needle insertion technique is an effective modification of PEIT.
    • This method significantly shortens the overall treatment period by reducing the number of sessions.
    • The multiple-needle approach offers a valuable improvement for PEIT, enhancing efficiency without compromising safety.