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Updated: Jul 5, 2026
06:49
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
Published on: November 20, 2016
[Congestive optic disks in the brain massive lesions]
Zhurnal Voprosy Neirokhirurgii Imeni N. N. Burdenko
|May 21, 2008
Summary
Papilledema (PE) affects over 30% of patients with brain lesions. Visual disturbances are common, with severity depending on the lesion type and papilledema stage.
Area of Science:
- Neurology
- Ophthalmology
- Neurosurgery
Context:
- Brain space-occupying lesions, including tumors, colloid cysts, and cholesteatomas, can lead to serious neurological complications.
- Papilledema, a sign of increased intracranial pressure, is a critical neuroophthalmologic finding in patients with brain lesions.
- Understanding the specific features of papilledema development is crucial for timely diagnosis and management of intracranial pathologies.
Purpose:
- To statistically analyze the neuroophthalmologic symptoms, specifically papilledema, in patients with various brain space-occupying lesions.
- To determine the frequency of papilledema in relation to lesion type, location, and patient demographics.
- To investigate the characteristics and determinants of visual disturbances associated with papilledema in this patient cohort.
Summary:
- A retrospective analysis of 962 patients with brain tumors, colloid cysts, or cholesteatomas revealed papilledema in 30.8% of cases.
- The incidence of papilledema was significantly influenced by histological pattern, lesion site, and patient age.
- Visual impairments, including reduced visual acuity and visual field defects, were present in over one-third of patients with papilledema, with severity correlating to the papilledema stage.
Impact:
- This study highlights the high prevalence of papilledema in patients with brain space-occupying lesions, emphasizing the need for thorough neuroophthalmologic examination.
- Findings underscore the importance of considering lesion characteristics and patient factors in predicting papilledema development and visual prognosis.
- The data provides valuable insights for neurosurgeons and ophthalmologists in managing patients with intracranial lesions and associated visual deficits.
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