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Direct AKAP-mediated protein-protein interactions as potential drug targets

C Hundsrucker1, E Klussmann

  • 1Leibniz-Institut für Molekulare Pharmakologie, Robert-Rössle-Str. 10, Berlin, Germany.

Handbook of Experimental Pharmacology
|May 21, 2008
PubMed
Summary

A-kinase-anchoring proteins (AKAPs) are crucial scaffolding proteins that organize cellular signaling. Disrupting AKAP interactions offers potential for novel cardiovascular and renal disorder treatments.

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