Related Experiment Video
Updated: Jul 5, 2026
Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates
Published on: March 7, 2014
A SERS-active nanocrystalline pd substrate and its nanopatterning leading to biochip fabrication
Thiruvelu Bhuvana1, Giridhar U Kulkarni
1Chemistry and Physics of Materials Unit and DST Unit on Nanoscience Jawaharlal Nehru Centre for Advanced Scientific Research Jakkur P O, Bangalore 560 064, India.
Abstract:
Nanocrystalline metallic Pd films have been produced by thermolysis of Pd hexadecanethiolate deposited on a Si surface. The particle size was in the range of 50-60 nm based on electron and atomic force microscopy. The Pd surface produced was found to be surface-enhanced Raman scattering (SERS) active with an enhancement factor of approximately 10(5). The electron-resist behavior of Pd thiolate is exploited in conceptualizing a prototype chip with patterned Pd regions that are SERS active, called "SERS bits", which host different biomolecules.
