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Related Experiment Video

Updated: Jul 5, 2026

Measuring Local Anaphylaxis in Mice
07:49

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Published on: October 14, 2014

[Recognizing anaphylaxis in the emergency department].

M Corvo1, A Martelli, L Gemellaro

  • 1Pronto Soccorso Pediatrico e UO Pediatria, Macedonio Melloni, Milano. mauriceco@libero.it

La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|May 22, 2008
PubMed
Summary

Severe acute allergic reactions in children visiting the emergency department are not well understood. This review aims to describe the characteristics of pediatric patients experiencing severe allergic reactions in emergency settings.

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Published on: September 14, 2018

Area of Science:

  • Pediatric Emergency Medicine
  • Allergy and Immunology
  • Clinical Pediatrics

Background:

  • Limited understanding exists regarding the patient profile for severe acute allergic reactions presenting to emergency departments.
  • Acute allergic reactions can manifest with diverse early symptoms, including gastrointestinal distress and respiratory compromise.
  • Sudden onset of severe symptoms like hypotension, circulatory failure, and cardiac arrest can occur, often linked to bronchospasm or laryngeal edema.

Purpose of the Study:

  • To characterize children presenting with severe acute allergic reactions in the emergency department setting.
  • To provide a descriptive overview of pediatric patients requiring emergency care for anaphylaxis.
  • To enhance the understanding of severe allergic reactions in pediatric emergency medicine.

Main Methods:

  • Literature review of studies focusing on pediatric emergency department visits for acute allergic reactions.
  • Synthesis of data on patient demographics, presenting symptoms, and clinical course.
  • Analysis of associated conditions and immediate management strategies.

Main Results:

  • Early symptoms in children can include swelling, sweating, restlessness, gastrointestinal upset, and respiratory signs like coughing or wheezing.
  • Severe reactions may rapidly progress to hypotension, circulatory failure, and cardiac arrest.
  • Bronchial spasm and laryngeal edema are frequently associated with critical events.

Conclusions:

  • Further research is needed to fully elucidate the characteristics of children with severe acute allergic reactions in emergency departments.
  • Recognizing early and severe symptoms is crucial for timely intervention in pediatric anaphylaxis.
  • This review highlights the critical nature of acute allergic reactions in pediatric emergency care.