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Visual perception and corollary discharge.

Marc A Sommer1, Robert H Wurtz

  • 1Department of Neuroscience and the Center for the Neural Basis of Cognition, University of Pittsburgh, A210 Langley Hall, Pittsburgh, PA 15260, USA. masommer@pitt.edu

Perception
|May 22, 2008
PubMed
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The brain uses corollary discharge signals from the midbrain to the frontal cortex to maintain stable vision during eye movements. This pathway ensures perception remains consistent despite retinal image shifts caused by saccades.

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Visual Perception

Background:

  • Perception relies on sensory input and brain state.
  • Stable visual perception during saccadic eye movements suggests brain compensation.
  • A hypothesis proposes corollary discharge signals mediate this compensation.

Purpose of the Study:

  • Identify the neural pathway and origin of corollary discharge signals for saccades.
  • Investigate the role of this pathway in visual compensation during eye movements.

Main Methods:

  • Review of evidence for corollary discharge signals in primate brains.
  • Analysis of experiments identifying a midbrain-to-cortex pathway via the thalamus.
  • Examination of two experiments testing the spatial, temporal, and necessity of the corollary signal.

Related Experiment Videos

Main Results:

  • A pathway for saccadic corollary discharge was identified: superior colliculus to medial dorsal thalamus to frontal eye fields.
  • The corollary discharge signal is spatially and temporally appropriate for altering frontal cortex neuron activity.
  • Inactivating this corollary pathway reduced compensation in frontal cortex neurons.

Conclusions:

  • This study specifies the organization of corollary discharge in the primate brain for the first time.
  • The identified circuit provides a model for understanding corollary activity in other systems and functions.
  • This pathway is crucial for maintaining stable visual perception during saccadic eye movements.