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Related Experiment Video

Updated: Jul 5, 2026

Live Imaging of Antifungal Activity by Human Primary Neutrophils and Monocytes in Response to A. fumigatus
12:29

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Published on: April 19, 2017

Hallucinations during voriconazole therapy.

Dimitrios I Zonios1, Juan Gea-Banacloche, Richard Childs

  • 1Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|May 22, 2008
PubMed
Summary
This summary is machine-generated.

Hallucinations are a common side effect of voriconazole treatment. Patients experiencing these visual disturbances should be reassured that this is a known drug effect.

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Area of Science:

  • Pharmacology
  • Clinical Toxicology
  • Neuroscience

Background:

  • Voriconazole is a widely used antifungal medication.
  • Adverse drug reactions require thorough characterization.
  • Central nervous system effects of antifungals warrant investigation.

Purpose of the Study:

  • To describe the characteristics of hallucinations in patients treated with voriconazole.
  • To raise awareness among healthcare providers about this potential side effect.

Main Methods:

  • Prospective natural history cohort study.
  • Inclusion of 12 patients who reported hallucinations.
  • Data collection on patient characteristics and voriconazole treatment.

Main Results:

  • Hallucinations were observed in 12 out of 72 patients treated with voriconazole.
  • The study characterizes the specific presentation of these hallucinations.

Conclusions:

  • Hallucinations are a notable complication of voriconazole therapy.
  • Clinicians should consider voriconazole-induced hallucinations in differential diagnoses.
  • Patient education and reassurance are important management strategies.