Synthesis of eudistomin C and E: improved preparation of the indole unit
Hiroaki Yamagishi1, Koji Matsumoto, Kotaro Iwasaki
1Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
Organic Letters
|May 24, 2008
Abstract:
An improved synthesis of the indole unit, a key intermediate for eudistomin C, was established utilizing Makosza's indole synthesis. A concise total synthesis of eudistomin E was achieved on the basis of the improved synthesis.
