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Identification of new major histocompatibility complex-A, -B, -C alleles in chimpanzees (Pan troglodytes)

L Caggiari1, M De Zorzi, G Ahlenstiel

  • 1Dipartimento di Oncologia Molecolare e Ricerca Traslazionale, Centro di Riferimento Oncologico, IRCCS National Cancer Insitute, Aviano, Italy.

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An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
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