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Erectile dysfunction predicts coronary heart disease in type 2 diabetes
Ronald Ching-Wan Ma1, Wing-Yee So, Xilin Yang
1Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
Journal of the American College of Cardiology
|May 24, 2008
Summary
Erectile dysfunction (ED) predicts new coronary heart disease (CHD) events in Chinese men with type 2 diabetes. Early ED screening can identify high-risk individuals for cardiovascular assessment.
Area of Science:
- Cardiology
- Endocrinology
- Urology
Background:
- Diabetes mellitus increases cardiovascular complication risk.
- Erectile dysfunction (ED) is linked to coronary heart disease (CHD) in cross-sectional studies, but prospective data are limited.
Purpose of the Study:
- To investigate the predictive value of ED for incident CHD events in Chinese men with type 2 diabetes.
Main Methods:
- A cohort of 2,306 men with type 2 diabetes and no prior cardiovascular disease were assessed.
- ED was defined using the 1992 National Institutes of Health Consensus Conference criteria.
- CHD events were tracked via hospital databases until 2005.
Main Results:
- 26.7% of participants had ED at baseline.
- The incidence of CHD events was significantly higher in men with ED (19.7/1000 person-years) compared to those without (9.5/1000 person-years).
- ED was an independent predictor of CHD events (HR 1.58, p=0.018) after adjusting for covariates.
Conclusions:
- In type 2 diabetic men without clinically evident cardiovascular disease, ED presence predicts new-onset CHD events.
- ED symptoms should be actively sought to identify high-risk individuals needing comprehensive cardiovascular evaluation.
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