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Updated: Jul 5, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
Bladder activation by selective stimulation of pudendal nerve afferents in the cat
Paul B Yoo1, John P Woock, Warren M Grill
1Department of Biomedical Engineering, Duke University, Hudson Hall, Room 136, Box 90281, Durham, NC 27708-0281, USA. paul.yoo@duke.edu
Abstract:
Bladder contractions evoked by pudendal nerve stimulation in both spinal intact and spinal transected cats support the possibility of restoring urinary function in persons with chronic spinal cord injury (SCI). However, electrically evoked bladder responses in persons with SCI were limited to transient contractions at relatively low pressures. This prompted the present study, which presents a detailed quantification of the responses evoked by selective stimulation of individual branches of the pudendal nerve at different stimulation frequencies. In spinal intact cats anesthetized with alpha-chloralose, selective frequency-dependent electrical activation of the sensory (2 Hz
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